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ANSES Warns on Sports Nutrition Overconsumption After Severe Adverse Event Report

France's ANSES highlights severe adverse events from excessive sports nutrition product intake, compelling manufacturers to review on-pack warnings and ingredient formulations for foreseeable misuse.

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Proteins Layer

Paris, France — 03 August 2026

The French Agency for Food, Environmental and Occupational Health & Safety (ANSES) has issued an opinion following a report of severe adverse health effects linked to excessive consumption of sports nutrition products. The case details a 54-year-old man, with pre-existing cirrhosis, who developed decompensated cirrhosis and acute renal failure, necessitating a liver transplant, after several weeks of exceeding manufacturers' recommended daily doses for a mass gainer and pure whey product. ANSES rated the link between the supplements and liver decompensation as 'very likely' and acute renal failure as 'likely', noting that daily protein intake of approximately 140g (1.6 g/kg body weight) combined with high levels of Vitamin A and B3 from the products contributed to liver toxicity and kidney stress.

Industry experts are now emphasising the sector's responsibility to address the prevalent 'more is better' mindset among consumers. Luca Bucchini, managing director at Hylobates Consulting, stated that 'scoop culture' makes extreme over-consumption a foreseeable behaviour, requiring formulators to consider extra warnings and carefully manage doses of specific vitamins. This perspective underscores the commercial imperative for brands to balance product efficacy with safety margins, particularly for active ingredients known to cause toxicity in high doses.

Ed Tooley, director and performance nutritionist, highlighted that consumers often lack awareness regarding overlapping ingredients across multiple blended products, inadvertently leading to excessive nutrient intake. While single-nutrient products mitigate this risk, multi-ingredient blends remain popular for convenience. Dan Richardson, founder of DRN Nutrition, acknowledged the rarity of such severe cases but noted that misuse often occurs among recreational gym-goers who stack supplements without considering total daily nutrient intake. Both underscore the need for clear communication on-pack regarding serving sizes and the implications of combining fortified products.

What this means for France

French manufacturers and brand owners must immediately review product labelling for sports nutrition, particularly mass gainers and protein powders, to ensure clear and unambiguous warnings against exceeding recommended dosages. Compliance with ANSES guidelines will necessitate a re-evaluation of Vitamin A and B3 inclusion levels to account for foreseeable consumer misuse, even if protein intake aligns with general sports nutrition recommendations. Brands should prepare for increased market surveillance by DGCCRF/ANSES and ensure robust adverse event reporting mechanisms are in place. Proactive measures, such as on-pack QR codes linking to detailed ingredient interaction information, could mitigate regulatory risk and improve consumer safety, securing market access in a scrutinised regulatory environment.

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